ESC: Ticagrelor Fails to Improve on Clopidogrel After Switch | Medpage Today

What his group also observed in the CHANGE DAPT study was that ticagrelor offered no reduction in ischemic events. This went against the findings of PLATO, a trial that reported fewer deaths and MIs associated with the drug in 2009 relative to clopidogrel. PLATO eventually led to guideline recommendations that ACS be treated with DAPT consisting of aspirin and ticagrelor in lieu of clopidogrel).

via ESC: Ticagrelor Fails to Improve on Clopidogrel After Switch | Medpage Today

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Dual antiplatelet therapy with prasugrel or ticagrelor versus clopidogrel in interventional cardiology. – PubMed – NCBI

For several years, clopidogrel plus aspirin has been the dual antiplatelet therapy (DAPT) of choice for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) with stent implantation.

via Dual antiplatelet therapy with prasugrel or ticagrelor versus clopidogrel in interventional cardiology. – PubMed – NCBI